| Patent Number |
BRPI0605850 A0 2007-03-13 |
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METHOD OF SELECTING PEPTIDES, PEPTIDES, METHOD AND KIT OF IDENTIFYING Mycobacterium Leprae INFECTIONS, PHARMACEUTICAL OR IMMUNOLOGICAL COMPOSITIONS CONTAINING Mycobacterium Leprae PEPTIDES OR SEQUENCES FUNCTIONALLY EQUIVALENT THERETO
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"method of selecting peptides, peptides, method and kit for identifying mycobacterium leprae infections, pharmaceutical or immunological compositions containing mycobacterium leprae peptides or sequences functionally equivalent thereto". the main objective of the present invention is to identify specific m. leprae, including those relating to latent forms or early phases of active disease. a first embodiment of the present invention relates to a method of selecting peptides derived from proteins or regions of proteins belonging to the genome of m. leprae with algorithms for detecting regions that combine with human histocompatibility molecules and capable of eliciting immune response in individuals exposed to m. leprae. a second embodiment of the present invention relates to peptides p37 to p94 (corresponding, respectively, to seq id no. 1 to seq id no. 58, or sequences functionally equivalent thereto). a third embodiment of the present invention relates to a method for the sensitive and specific detection of m. leprae infections by the following steps: (a) collecting the sample to be examined; (b) extracting the biological material of interest from the sample obtained in (a); (c) contacting the biological material from step (b) with at least one of the peptides.
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©Questel
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| FamPat family |
| Publication Number |
Type |
Publi.Date |
Links |
 |
BRPI0605850 |
A0 |
2007-03-13 |
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STG: |
(A0) Application filed, as announced in the Gazette published by this office |
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AP: |
2006BR-0005850 |
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BRPI0605850 |
A |
2008-08-12 |
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STG: |
(A) Published application |
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AP: |
2006BR-0005850 |
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BRPI0605850 |
B1 |
2018-02-06 |
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STG: |
(B1) Granted patent / Granted pipeline patent |
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AP: |
2006BR-0005850 |
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BRPI0605850 |
B8 |
2021-07-27 |
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STG: |
(B8) Modified first page patent/pipeline patent |
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AP: |
2006BR-0005850 |
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| First Date of Grant |
2018-02-06 |
| Inventor |
GERALDO MOURA BATISTA PEREIRA
HAZEL MARGUERITE DOCKRELL
JOHN SPENCER STEWART
MARIA CRISTINA VIDAL PESSOLANI
MÁRCIA VALÉRIA BRANDÃO DOS SANTOS MARTINS
MÔNICA CRISTINA BRANDÃO DOS SANTOS LIMA
PATRICK JOSEPH BRENNAN |
| All applicant/assignee |
Fundação Oswaldo Cruz ([BR])
FUNDACAO OSWALDO CRUZ
FUNDACAO OSWALDO CRUZ ([BR])
Cruz Fundação Oswaldo ([BR]) |
| Priority Details |
2006BR-0005850 2006-12-14 |
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©Questel
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